The Levels of Secretory Leukocyte Protease Inhibitor and .ALPHA.1-Protease Inhibitor in Gingival Crevicular Fluid from Adult Periodontal Patients.

Secretory leukocyte protease inhibitor as an indicator of periodontal disease

Immunoregulatory role of secretory leukocyte protease inhibitor in allergic asthma

Background Asthma is a complex and multi-factorial inflammatory disease [1]. It is one of the most common chronic diseases among children and adolescents [2]. Secretory leukocyte protease inhibitor (SLPI) has shown higher levels in asthmatic patients and its function as an anti-inflammatory protein has been documented in respiratory diseases [3,4]. However, its role in the immunomodulation of t...

Human alveolar macrophages express elafin and secretory leukocyte protease inhibitor.

Elafin and secretory leukocyte protease inhibitor (SLPI) are two structurally related serine protease inhibitors present in the lung. The cellular origin of elafin in the alveolar space is unknown. It has been suggested that at least one alveolar leukocyte population express elafin. We therefore postulated that the alveolar macrophage, as the most numerous leukocyte in the alveolar space, expre...

Secretory leukocyte protease inhibitor antagonizes paclitaxel in ovarian cancer cells.

PURPOSE Ovarian cancer recurrence with the development of paclitaxel resistance is an obstacle to long-term survival. We showed that secretory leukocyte protease inhibitor (SLPI) is a survival factor for ovarian cancer. We hypothesize that SLPI may antagonize paclitaxel injury. EXPERIMENTAL DESIGN Differential SLPI induction in response to paclitaxel and in response to stable forced expressio...

Secretory Leukocyte Protease Inhibitor Potent Antimycobacterial Activity of Mouse